Consider Room Rewards
Loot and Currency: Does the room have chests, fountains, or Path of Exile 2 Currency merchant access nearby?

Experience and Progress: Clearing enemies might unlock access to better paths or bonus rooms.

Sacred Water Fountains: Prioritize rooms with fountains as their rewards are critical.

Honor Shrines: Some combat rooms contain Honor restoration, increasing their value.

Rooms with guaranteed or high-value rewards generally justify taking more risk.

Strategies for Managing Risk in Combat Rooms
1. Prepare Before Engagement
Use ranged or crowd-control skills to soften enemy packs before closing in.

Position yourself to avoid traps or environmental hazards.

Activate defensive Boons or Relics in anticipation.

2. Prioritize Targets
Focus on enemies that deal the most damage or have dangerous abilities.

Eliminate casters or ranged foes quickly to reduce incoming damage.

Use area-of-effect skills to clear groups efficiently.

3. Use Tactical Retreats
If overwhelmed, retreat to safer areas to regenerate health or reposition.

Don’t hesitate to abandon a fight if the risk of Honor loss or death is high.

When to Skip Combat Rooms
Not all combat rooms are worth the risk:

If your Honor or health is critically low and there are no nearby Honor Shrines or Sacred Water Fountains.

When rewards are minimal or uncertain.

If alternative paths with safer or more rewarding rooms exist.

When time constraints or run length suggest preserving resources for later.

Skipping rooms can be a smart choice, preserving your progress and POE 2 Exalted Orbs for sale resources for tougher, more rewarding encounters.